Malaria Cycle

The
complete cycle of the human malaria parasite, consist principally of two stages
namely:
Ø  A period of development within mosquitoes when the
infective spororozoites are formed in the blood of mosquitoes by union of male
and female gametocytes. This stage is called the sexual stage.

Ø  A period of infection in man. These are cycles
which involve erythrocytic cycle and exoerythrocytic cycle. It is known as
asexual stage. When mosquito bites an individual with malaria it then feeds on
the blood. The male and female gametocytes of plasmodium in the human blood
enter the mosquito’s stomach where they unite and multiply and form sporozoites
which develop in 8 – 36 hours. Sporozoites enter the insect’s salivary glands
and inject into another human during mosquito bites. Sporozoites quickly enter
the new hosts liver remain there for 7 – 9 days and further developed to
mosquitoes. Merozoites are then liberated into blood stream and parasitize the
red blood cell.
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