Due to the presence of Iso – antibodies against non –
self blood group antigens, individual of type A blood group immediately rise
anti B antibodies against B. If transfused with blood from B group, the anti- A
antibodies bound to B antigen in the red cells and cause complement. To blood
group B and O, however only AB blood
group does not have anti – A and B Iso – antibodies, this is because both A and
B antigens are present in the cell. (Mohandas and Narla, 2005).
self blood group antigens, individual of type A blood group immediately rise
anti B antibodies against B. If transfused with blood from B group, the anti- A
antibodies bound to B antigen in the red cells and cause complement. To blood
group B and O, however only AB blood
group does not have anti – A and B Iso – antibodies, this is because both A and
B antigens are present in the cell. (Mohandas and Narla, 2005).
The table below summarizes the antibodies and antigen
in the blood groups.
in the blood groups.
Phenotype |
Red blood cell surface antigens |
Serum Antibodies |
A |
A |
Anti – B |
O |
_ |
Anti – A, Anti –B |
B |
B |
Anti – A |
AB |
A, B |
_ |
(Source: Mohandas and Narla, 2005).
