Due to the presence of Iso – antibodies against non –
self blood group antigens, individual of type A blood group immediately rise
anti B antibodies against B. If transfused with blood from B group, the anti- A
antibodies bound to B antigen in the red cells and cause complement. To blood
group B and O, however only AB blood
group does not have anti – A and B Iso – antibodies, this is because both A and
B antigens are present in the cell. (Mohandas and Narla, 2005).
self blood group antigens, individual of type A blood group immediately rise
anti B antibodies against B. If transfused with blood from B group, the anti- A
antibodies bound to B antigen in the red cells and cause complement. To blood
group B and O, however only AB blood
group does not have anti – A and B Iso – antibodies, this is because both A and
B antigens are present in the cell. (Mohandas and Narla, 2005).
The table below summarizes the antibodies and antigen
in the blood groups.
in the blood groups.
|
Phenotype
|
Red
blood cell surface antigens |
Serum
Antibodies |
|
A
|
A
|
Anti – B
|
|
O
|
_
|
Anti – A, Anti –B
|
|
B
|
B
|
Anti – A
|
|
AB
|
A, B
|
_
|
(Source: Mohandas and Narla, 2005).
