Blood Group Antigens

An
antigen is a substance which when introduced into the body stimulates the
production of corresponding antibody and which reacts with antibody in some observable
manner such as agglutination, sensitization and haemolysis. Antigens are larger
molecular substances usually protein but sometimes combined with polysaccharide
component. The antigens occur on the surface of the red blood cell (RBC) in a
large proportion of human beings. Examples of blood group antigens are A and B.
the blood group antigens include substance on the red blood cell (RBC) and on
the other blood constituents such as leucocytes, platelet and plasma. The blood
constituent antigens which are governed by a single gene or group of genes are
inherited as groups. Most blood group antigens are usually glycoprotein or
glycolipids in nature (Benjamin and Pierce, 2008).
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