Overview on vitamin A deficiency

Vitamin A
deficiency is a condition which occur when there is lack
of vitamin A in the blood or tissues. Vitamin A cannot be made by the human
body and so it is an essential part of the diet. Vitamin A is important for
healthy eyes, good eyesight (vision), healthy skin and to help you fight
infections. Foods that contain vitamin A include liver, milk, eggs and
fish-liver oils.

Low levels or lack of Vitamin A in a human body
causes Vitamin A deficiency and it is the number one cause of what is known as
preventable blindness in children and severe visual impairment. Vitamin A
deficiency also increases the risk of death in infants.
It is known to cause night blindness in pregnant
women and escalates the chances of maternal mortality. It is usually the third
trimester when the nutritional demands of both the mother and the unborn child
become the highest. During this time if the body is suffering from Vitamin A
deficiency then the mother can be at severe risk of night blindness.Vitamin A,
therefore, is necessary for the body mainly to maintain normal visual function.
However it has become evident that Vitamin A deficiency
can also lead to the body’s growing inability to fight against infections. That
will eventually result in many other illnesses and diseases. Children who
suffer from it can even die from measles, extreme diarrhea or respiratory
infection. Even a slight deficiency can affect them in the development of bones
and their overall growth
Symptoms
of vitamin A deficiency
There are many symptoms of vitamin A deficiency
through which one can detect low levels of Vitamin A in the body. These
symptoms are as follows,
  • Reduced
    vision in the night or dim light; which means that they will not be able
    to distinguish outlines of images in reduced illumination. They might
    however still go on to see normally during day light hours until the night
    blindness turns into some other severe form.
  • Dry
    eyes which could also lead to severe form of night blindness in which the
    outer membrane of the eye, known as conjunctiva loses its goblet cells.
    These cells perform to release mucus in the eye, to keep it lubricated.
    The loss of goblet cells results in this condition in which the eye can no
    longer produce tears. These dead or lost cells can even accumulate on the
    outer layer of the eye resembling a form of debris. This debris can easily
    lead to blindness or any other infection.
  • Eye
    inflammation can also result from vitamin A deficiency. Because of the
    inflammation, the eyelids and surrounding tissues along with eyes can get
    affected. This may include corneal inflammation as well.
  • The
    child or adult may experience susceptibility towards respiratory infection
    and urinary infections.
  • Growth
    can be halted in children due to vitamin A deficiency.
  • Skin
    might also show signs of Vitamin A deficiency. For example it may get
    rough and/or dry.

 

Causes of vitamin A deficiency

The
following are some of the direct and indirect causes of Vitamin A deficiency.
  • The biggest reason behind Vitamin A deficiency
    is malnutrition. People who have a low intake of animal foods usually are
    at a risk of this deficiency. Animal food products and some vegetables are
    a rich source of Vitamin A.
  • Breast milk contains good amount of Vitamin A
    for newborns. The mothers who don’t breast feed their children put them at
    a risk of developing Vitamin A deficiency.
  • If a pregnant or lactating mother is Vitamin A
    deficient then the newborn baby is very likely going to be vitamin A
    deficient as well.
  • Mal-absorption of vitamin A by the body can
    also lead to its deficiency. It can be due to sprue, celiac disease,
    obstructive jaundice, cirrhosis, giardiasis, cystic fibrosis or an over
    use of mineral oil as laxative.
  • Over excretion of urine is also known to cause
    Vitamin A deficiency. Massive excretion can be caused by tuberculosis, urinary
    tract infections (UTIs), cancer, pneumonia and nephritis.
  • Lack of storage ability of Vitamin A by the
    body resulting from hepatic disease also causes vitamin A deficiency.

 

Treatment of vitamin A deficiency

Vitamin
A deficiency can be treated in its early stage when the condition has not
worsened. Hence early diagnosis is very important. If detected early, it can be
treated through the following measures.
  • A diet which is rich in Vitamin A is usually
    the treatment and the best prevention method of vitamin A deficiency.
    Liver, kidney, milk, cheese, cream and butter are rich sources of Vitamin
    A. Vitamin A can also be absorbed in the body through Carotene which is
    found in vegetables which have dark green vegetables. Vitamin A is also
    said to be present in fruits and vegetables that are yellow and orange in
    color.
  • Food fortification also helps improve food
    quality. A lot of food stuff is fortified with Vitamin A to counteract the
    vitamin A deficiency. Both dry and oily forms of retinol acetates, and
    retinal esters can be added to fortify the product with Vitamin A. They
    are usually added to cooking oil and margarine.
  • Other than the oil and margarine, Vitamin A is
    also added to sugar, cereals and milk/milk powder. If vitamin A deficiency
    is detected then it is imperative that one should start taking food
    products that are naturally rich in Vitamin A and those that have been
    fortified with it.
  • Vitamin A can also be taken through medication
    in oral and injectable forms. Orally they can be taken as supplements
    after meals or with meals.
Conclusion
Vitamin A
deficiency leads to blindness and several other adverse health conditions which
can be prevented by adequate nutrition (balanced diet). Also, early diagnosis
and treatment is very important to prevent the condition from getting worse;
since it can only be managed effectively at its early stage.
References
Black, R. E. (2008). Maternal and child undernutrition: global and
regional exposures and health consequences, The
Lancet, 371(9608),
253
Latham,
M. E. (1997). Human Nutrition in the Developing World (Fao Food and Nutrition
Paper). Food & Agriculture Organization of the United
Sommer,
A. (1995).Vitamin a Deficiency and Its Consequences: A Field Guide to Detection
and Control. Geneva: World Health Organization
Stoltzfus,
R.J.Hakimi, M. & Miller,K.W. (1993).High dose vitamin A supplementation of
breast-feeding Indonesian mothers: effects on the vitamin A status of mother
and infant. J. Nutr., 123 (4),
666–75.
Tang, G.,
Qin, J., Dolnikowski, G. G., Russell,R.M. &Grusak, M. A. (2005).Spinach or
carrots can supply significant amounts of vitamin A as assessed by feeding with
intrinsically deuterated vegetables.The American Journal of Clinical Nutrition,
82 (4), 821–8.
World Health Organization (2006).Global
prevalence of vitamin A deficiency in populations at risk 1995–2005.
WHO
global database on vitamin A deficiency.
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