New measures for TB eradication unveiled by WHO

New measures for the eradication of tuberculosis (TB) had been unveiled by the new guidelines issued by the World Health Organisation (WHO) for the treatment if multi-drug resistant TB (MDR-TB). The WHO on Wednesday 20th March, 2019 released a statement on the treatment of TB by shifting to fully oral regimes for the treatment of people with MDR-TB. According to the WHO, the new treatment course is more effective and is less likely to provoke adverse side effects.

TB is potentially serious infectious disease that affects the lungs although it can spread to other organs which is caused by bacteria that spread through the air from person to person. If not treated properly TB can be a fatal disease.

Experiences have shown that some TB patients develop MDR-TB, which is more difficult to treat. MDR-TB is a particular type of drug-resistant TB. MDR-TB  means that the TB bacteria in a person infected are resistant to two of the most important TB drugs- isoniazid (INH) and rifampicin (RMP).

Before this new announcement, treatment for MDR-TB (drug-resistant TB) had often required a large number of drugs to be taken for up to two years. Also, the drugs had often been noticed to cause severe side effects in patients. So, various efforts were made to develop shorter regimens which were easier to take by patience with MDR-TB.

The WHO recommended in May 2016 that there should be a major change to the treatment for MDR-TB (drug-resistant TB) with shorter regimens being made available for many patients. WHO however in its new guideline recommended backing up treatment with active monitoring of drug safety and providing counselling support to help patients complete their treatments. WHO said the recommendations are part of a larger package of actions designed to help countries increase the pace of progress to end TB and released in advance of World TB Day.

The World TB Day is observed March 24 each year. The day is set aside to create public awareness about the devastating health, social and economic consequences of the disease. The theme of this year’s World TB Day, “It’s time to end TB.”

According to the WHO Director-General, Tedros Adhanom, the board is highlighting the urgent need to translate commitments made at the 2018 UN High-Level Meeting on TB into actions that ensure everyone who needs TB care can get it. He said since 2000, 54 million have been treated, and TB deaths fell by one third, but 10 million people still fall ill with TB every year, with too many missing on vital care. TB remains the world’s deadliest infectious killer disease.

Each year, nearly 4,500 people lose their lives to TB and about 30,000 people fall ill with the disease. Nigeria still ranks among countries with the highest burden of the diseases. At least 18 Nigerians die from the disease every hour. With only 25 per cent detection rate, Nigeria is classified among countries with a high burden for TB, TB/HIV and MDR-TB and currently ranks sixth globally and first in Africa. Nigeria contributes nine per cent to the global 3.6 million missing TB cases, coming behind only India and Indonesia with 26 per cent and 11 per cent respectively. An estimated 418,000 new TB cases occurred in Nigeria in 2018.

The new treatment regimen for the treatment of MDR-TB unveiled by the WHO is designed to help countries close gaps in care ensuring no one is left behind. The Director WHO’s Global TB Programme, Tereza Kasaeva, said that this is a set of pragmatic actions that countries can use to accelerate progress and act on the high-level commitments made in the first-ever UN High-Level Meeting on TB last September. He added that on 22nd March 2019, key partners will come together at a World TB Day symposium at WHO in Geneva to develop a collaborative multi-stakeholder and multisectoral platform to accelerate actions to end TB. WHO will also present the new package at the meeting.

Below are some of the tips on TB

  1. The disease is treatable and curable
  2. DR-TB is common among persons who do not take their TB drugs regularly
  3. In a person infected with both HIV and TB, the HIV weakens the immune system so inactive TB germs are more likely to become active leading to an active case of T.
  4. HIV increases the chances of re-infection and relapse in persons treated for TB
  5. All TB patients and suspected should be tested for HIV
  6. When you are coughing for more than two weeks, go for a TB test.
  7. It is an airborne disease. It spreads when an infected person coughs or sneezes.
  8. TB is partly preventable by vaccine
  9. Most people infected with TB bacteria don’t have symptoms.
  10. When symptoms do occur, they usually include a cough (sometimes blood-tinged), weight loss, night sweats and fever.
  11. Treatment isn’t always required for those without symptoms. Patients with active symptoms will require a long course of treatment involving multiple antibiotics.
  12. Nigeria has a free TB toll number where you can make all necessary enquiries about the disease. Toll number is 08002255282.
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