Patterns of tuberculosis infections

There are two major patterns of disease with tuberculosis, they are;

  1. Primary tuberculosis: This is seen as an initial infection usually in children, the initial focus of infection is a small sub-pleural granuloma accompanied by granulomatous hilar lymph node infection. In nearly all cases these granulomas resolve and there is no further of the infection.
  2. Secondary tuberculosis: This is seen mostly in adults as a reactivation of previous infection (or re-infection), particularly when health patterns declines. The granulomatous inflammation is much more florid and widespread, typically the upper lung lobes are most affected and cavitations’ can occur.
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